Chlortetracycline HCl, USP Grade

Request Lot Specific COA

View Current Lot COA

Citation Search Tool

Description

Chlortetracycline, isolated from Streptomyces aureofaciens, was the first tetracycline antibiotic discovered. It has shown the most efficacy against gram-positive organisms, but is also effective on a variety of gram-negative bacteria. Resistance to chlortetracycline arises from a loss of cell wall permeability.

Tetracyclines are antibiotics made up of a four-ring system. They bind the 30s ribosomal subunit, preventing the aminoacyl-tRNA from attaching to the A site. Consequently, protein synthesis is inhibited.


Product Specifications
Chlortetracycline HCl, USP Grade
7-Chlorotetracycline, USP Grade

Formula: C22H23ClN2O8 ∙ HCl

MW: 515.34 g/mol

Storage/Handling: Store at -20°C. Protect from light.

PubChem Chemical ID: 54684459

Chlortetracycline HCl, USP Grade

View Sizes & Pricing

Catalog Number:
C-840-25
CAS Number:
64-72-2
$147.00

For research use only. Not for food, drug, household, or cosmetic use.
Availability:
2-3 Weeks
Shipping:
$14.99 Ground shipping (In continental US only.)

    Description

    Chlortetracycline, isolated from Streptomyces aureofaciens, was the first tetracycline antibiotic discovered. It has shown the most efficacy against gram-positive organisms, but is also effective on a variety of gram-negative bacteria. Resistance to chlortetracycline arises from a loss of cell wall permeability.

    Tetracyclines are antibiotics made up of a four-ring system. They bind the 30s ribosomal subunit, preventing the aminoacyl-tRNA from attaching to the A site. Consequently, protein synthesis is inhibited.


    Product Specifications
    Chlortetracycline HCl, USP Grade
    7-Chlorotetracycline, USP Grade

    Formula: C22H23ClN2O8 ∙ HCl

    MW: 515.34 g/mol

    Storage/Handling: Store at -20°C. Protect from light.

    PubChem Chemical ID: 54684459

    Product Specifications

    Catalog ID: C-840
    CAS #: 64-72-2
    MW: 515.34 g/mol
    Storage/handling: Store at -20°C.
    PubChem Chemical ID: 54682468
    IUPAC Name: (4S,4aS,5aS,6S,12aR)-7-chloro-4-(dimethylamino)-1,6,10,11,12a-pentahydroxy-6-methyl-3,12-dioxo-4,4a,5,5a-tetrahydrotetracene-2-carboxamide;hydrochloride
    InChI: InChI=1S/C22H23ClN2O8.ClH/c1-21(32)7-6-8-15(25(2)3)17(28)13(20(24)31)19(30)22(8,33)18(29)11(7)16(27)12-10(26)5-4-9(23)14(12)21;/h4-5,7-8,15,26-27,30,32-33H,6H2,1-3H3,(H2,24,31);1H/t7-,8-,15-,21-,22-;/m0./s1
    InChIKey: QYAPHLRPFNSDNH-MRFRVZCGSA-N
    SMILES: CC1(C2CC3C(C(=O)C(=C(C3(C(=O)C2=C(C4=C(C=CC(=C41)Cl)O)O)O)O)C(=O)N)N(C)C)O.Cl

    Featured Articles

      Login

      Forgot your password?

      Don't have an account yet?
      Create account