Econazole Nitrate

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Description

Econazole Nitrate is a broad-spectrum antimycotic imidazole antifungal targeting the cell membrane of fungi. It increases cell permeability via ergosterol synthesis inhibition. It is useful against fungi that cause Tinea especially Trichophyton and Microsporum species. It can be used to study platelet serotonin uptake and the synthesis of prostanoids.

Econazole Nitrate is often used in clinical in vitro tests known as antimicrobial susceptibility tests or ASTs to determine their efficacy against certain bacterial species. They are tested against gram-negative and gram-positive bacteria using panels, discs, and MIC strips by medical microbiologists. ASTs decrease the risk of using an antibiotic against bacteria exhibiting resistance to it, and the results are used in clinical settings to determine which antibiotic(s) to prescribe for various infections.

Product Specifications
Econazole Nitrate Salt

MOLECULAR BIOLOGY GRADE

Formula: C18H15Cl3N2O ∙ HNO3

MW: 444.70 g/mol

Storage/Handling: Store at 2-8 °C. This product is light sensitive.
Econazole Nitrate is soluble in DMSO.

PubChem Chemical ID: 68589

Econazole Nitrate

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Catalog Number:
E-200-5
CAS Number:
24169-02-6
$73.00

For research use only. Not for food, drug, household, or cosmetic use.
Availability:
2-3 Weeks
Shipping:
$14.99 Ground shipping (In continental US only.)

    Description

    Econazole Nitrate is a broad-spectrum antimycotic imidazole antifungal targeting the cell membrane of fungi. It increases cell permeability via ergosterol synthesis inhibition. It is useful against fungi that cause Tinea especially Trichophyton and Microsporum species. It can be used to study platelet serotonin uptake and the synthesis of prostanoids.

    Econazole Nitrate is often used in clinical in vitro tests known as antimicrobial susceptibility tests or ASTs to determine their efficacy against certain bacterial species. They are tested against gram-negative and gram-positive bacteria using panels, discs, and MIC strips by medical microbiologists. ASTs decrease the risk of using an antibiotic against bacteria exhibiting resistance to it, and the results are used in clinical settings to determine which antibiotic(s) to prescribe for various infections.

    Product Specifications
    Econazole Nitrate Salt

    MOLECULAR BIOLOGY GRADE

    Formula: C18H15Cl3N2O ∙ HNO3

    MW: 444.70 g/mol

    Storage/Handling: Store at 2-8 °C. This product is light sensitive.
    Econazole Nitrate is soluble in DMSO.

    PubChem Chemical ID: 68589

    Product Specifications

    Catalog ID: E-200
    CAS #: 24169-02-6
    Formula: C18H15Cl3N2O∙HNO3
    MW: 444.70 g/mol
    Grade: MOLECULAR BIOLOGY GRADE
    Storage/handling: Store at 4°C.
    PubChem Chemical ID: 68589
    IUPAC Name: 1-[2-[(4-chlorophenyl)methoxy]-2-(2,4-dichlorophenyl)ethyl]imidazole;nitric acid
    InChI: InChI=1S/C18H15Cl3N2O.HNO3/c19-14-3-1-13(2-4-14)11-24-18(10-23-8-7-22-12-23)16-6-5-15(20)9-17(16)21;2-1(3)4/h1-9,12,18H,10-11H2;(H,2,3,4)
    InChIKey: DDXORDQKGIZAME-UHFFFAOYSA-N
    SMILES: C1=CC(=CC=C1COC(CN2C=CN=C2)C3=C(C=C(C=C3)Cl)Cl)Cl.[N+](=O)(O)[O-]

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