Mitoxantrone HCl

Description

Mitoxantrone HCl is an anthracenedione anti-cancer agent. It functions by intercalating between DNA and causing double-stranded breaks. This inhibits T-cell, B-cell, and macrophage division and prevents DNA repair and synthesis. It has been shown to be effective against breast cancers, leukemias, and non-Hodgkin’s lymphoma. It also exhibits immunosuppressive activity by inducing apoptosis in antigen-presenting T-cells and is an immune system regulator in multiple sclerosis.

Product Specifications
Mitoxantrone HCl
Mitoxantrone Hydrochloride

MOLECULAR BIOLOGY GRADE

Formula: C22H28N4O6 ∙ 2HCl

MW: 517.40 g/mol

Storage/Handling: Store at 2-8°C.

PubChem Chemical ID: 51082

Mitoxantrone HCl

View Sizes & Pricing

Catalog Number:
M-910-50
CAS Number:
70476-82-3
$144.00

For research use only. Not for food, drug, household, or cosmetic use.
Availability:
2-3 Weeks
Shipping:
$14.99 Ground shipping (In continental US only.)

    Description

    Mitoxantrone HCl is an anthracenedione anti-cancer agent. It functions by intercalating between DNA and causing double-stranded breaks. This inhibits T-cell, B-cell, and macrophage division and prevents DNA repair and synthesis. It has been shown to be effective against breast cancers, leukemias, and non-Hodgkin’s lymphoma. It also exhibits immunosuppressive activity by inducing apoptosis in antigen-presenting T-cells and is an immune system regulator in multiple sclerosis.

    Product Specifications
    Mitoxantrone HCl
    Mitoxantrone Hydrochloride

    MOLECULAR BIOLOGY GRADE

    Formula: C22H28N4O6 ∙ 2HCl

    MW: 517.40 g/mol

    Storage/Handling: Store at 2-8°C.

    PubChem Chemical ID: 51082

    Product Specifications

    Catalog ID: M-910
    CAS #: 70476-82-3
    Formula: C22H28N4O6∙2HCl
    MW: 517.40 g/mol
    Grade: MOLECULAR BIOLOGY GRADE
    Storage/handling: Store at 4°C.
    PubChem Chemical ID: 51082
    IUPAC Name: 1,4-dihydroxy-5,8-bis[2-(2-hydroxyethylamino)ethylamino]anthracene-9,10-dione;dihydrochloride
    InChI: InChI=1S/C22H28N4O6.2ClH/c27-11-9-23-5-7-25-13-1-2-14(26-8-6-24-10-12-28)18-17(13)21(31)19-15(29)3-4-16(30)20(19)22(18)32;;/h1-4,23-30H,5-12H2;2*1H
    InChIKey: ZAHQPTJLOCWVPG-UHFFFAOYSA-N
    SMILES: C1=CC(=C2C(=C1NCCNCCO)C(=O)C3=C(C=CC(=C3C2=O)O)O)NCCNCCO.Cl.Cl

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