Description
Oxytetracycline is a tetracycline antibiotic derived from Streptomyces rimosus. It targets gram-positive and gram-negative bacteria and several Mycoplasma species. Oxytetracycline has been used to study its resistance gene, otrA and in fluorescence analysis of liver cells.
Additionally, oxytetracycline is used as a selective agent in OGYE, a selective medium for yeasts and molds. It has been used to prevent fire blight in apples and pears and has been shown to be a better alternative to streptomycin against fire blight disease.
Tetracyclines are antibiotics made up of a four-ring system. They bind the 30s ribosomal subunit, preventing the aminoacyl-tRNA from attaching to the A site. Consequently, protein synthesis is inhibited. Resistance is conferred through active efflux, protection of ribosomes, or tetracycline inactivation.
Product Specifications
Oxytetracycline Dihydrate
MOLECULAR BIOLOGY GRADE
Formula: C22H24N2O9 ∙ 2H2O
MW: 496.46 g/mol
Storage/Handling: Store at 2-8 °C. This product is light sensitive and is soluble in acids and bases (pH 1.2 = 31 mg/mL; pH 9.0 = 38 mg/mL).
PubChem Chemical ID: 54680691
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