Description
Oxytetracycline is a tetracycline antibiotic derived from Streptomyces rimosus. It targets gram-positive and gram-negative bacteria and several Mycoplasma species. Oxytetracycline has been used to study its resistance gene, otrA and in fluorescence analysis of liver cells.
Additionally, oxytetracycline is used as a selective agent in OGYE, a selective medium for yeasts and molds. It has been used to prevent fire blight in apples and pears and has been shown to be a better alternative to streptomycin against fire blight disease.
Tetracyclines are antibiotics made up of a four-ring system. They bind the 30s ribosomal subunit, preventing the aminoacyl-tRNA from attaching to the A site. Consequently, protein synthesis is inhibited. Resistance is conferred through active efflux, protection of ribosomes, or tetracycline inactivation.
Oxytetracycline HCl is more soluble in aqueous solution than oxytetracycline dihydrate.
Product Specifications
Oxytetracycline HCl
MOLECULAR BIOLOGY GRADE
Formula: C 22H24N2O9 ∙ HCl
MW: 496.89 g/mol
Storage/Handling: Store under inert gas at <4°C.
NOTE: Concentrated aqueous solutions at neutral pH hydrolyze and precipitate crystals of oxytetracycline.
PubChem Chemical ID: 54680782
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