Roxithromycin

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Description

Roxithromycin is a macrolide antibiotic and derivative of erythromycin. It targets both gram-negative and gram-positive bacteria and has shown strong efficacy against Legionella pneumophila and a variety of oral pathogens. Additionally, roxithromycin inhibits the activation of NADPH oxidase and promotes neutrophil apoptosis.

Macrolide antibiotics are composed of a macrocyclic lactone ring attached to one or more deoxy sugars. They inhibit bacterial protein synthesis by irreversibly binding the P site of the 50s ribosome, preventing peptide bond formation and translocation.


Product Specifications
Roxithromycin

MOLECULAR BIOLOGY GRADE

Formula: C41H76N2O15

MW: 837.05 g/mol

Storage/Handling: Store at 2-8°C.

PubChem Chemical ID: 5480431

Roxithromycin

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Catalog Number:
R-500-5
CAS Number:
80214-83-1
$75.00

For research use only. Not for food, drug, household, or cosmetic use.
Availability:
2-3 Weeks
Shipping:
$14.99 Ground shipping (In continental US only.)

    Description

    Roxithromycin is a macrolide antibiotic and derivative of erythromycin. It targets both gram-negative and gram-positive bacteria and has shown strong efficacy against Legionella pneumophila and a variety of oral pathogens. Additionally, roxithromycin inhibits the activation of NADPH oxidase and promotes neutrophil apoptosis.

    Macrolide antibiotics are composed of a macrocyclic lactone ring attached to one or more deoxy sugars. They inhibit bacterial protein synthesis by irreversibly binding the P site of the 50s ribosome, preventing peptide bond formation and translocation.


    Product Specifications
    Roxithromycin

    MOLECULAR BIOLOGY GRADE

    Formula: C41H76N2O15

    MW: 837.05 g/mol

    Storage/Handling: Store at 2-8°C.

    PubChem Chemical ID: 5480431

    Product Specifications

    Catalog ID: R-500
    CAS #: 80214-83-1
    Formula: C41H76N2O15
    MW: 837.05 g/mol
    Grade: MOLECULAR BIOLOGY GRADE
    Storage/handling: Store at 4°C.
    PubChem Chemical ID: 6915744
    IUPAC Name: (3R,4S,5S,6R,7R,9R,10E,11S,12R,13S,14R)-6-[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-14-ethyl-7,12,13-trihydroxy-4-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-10-(2-methoxyethoxymethoxyimino)-3,5,7,9,11,13-hexamethyl-oxacyclotetradecan-2-one
    InChI: InChI=1S/C41H76N2O15/c1-15-29-41(10,49)34(45)24(4)31(42-53-21-52-17-16-50-13)22(2)19-39(8,48)36(58-38-32(44)28(43(11)12)18-23(3)54-38)25(5)33(26(6)37(47)56-29)57-30-20-40(9,51-14)35(46)27(7)55-30/h22-30,32-36,38,44-46,48-49H,15-21H2,1-14H3/b42-31+/t22-,23-,24+,25+,26-,27+,28+,29-,30+,32-,33+,34-,35+,36-,38+,39-,40-,41-/m1/s1
    InChIKey: RXZBMPWDPOLZGW-XMRMVWPWSA-N
    SMILES: CCC1C(C(C(C(=NOCOCCOC)C(CC(C(C(C(C(C(=O)O1)C)OC2CC(C(C(O2)C)O)(C)OC)C)OC3C(C(CC(O3)C)N(C)C)O)(C)O)C)C)O)(C)O

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