Description
Sulfamethazine is broad-spectrum sulfonamide antibiotic targeting bacteria causing bronchitis and urinary tract infections. It is used in disposition and depletion studies of kinetics and to develop procedures used for quantification. Sulfamethazine is also an inducer of CYP3A4.
Sulfonamide antibiotics are derived from a chemical called sulfanilamide. They function through inhibiting the conversion of p-aminobenzoic acid to dihydropteroate, an essential step in the synthesis of folic acid. By preventing the production of folate in bacteria, the sulfonamide antibiotics ultimately suppress bacterial DNA replication.
Product Specifications
Sulfamethazine
MOLECULAR BIOLOGY GRADE
Formula: C12H14N4O2S
MW: 278.33 g/mol
Storage/Handling: Store at 2-8°C.
This product is light sensitive.
PubChem Chemical ID: 5327