Description
Cefpirome is a fourth generation cephalosporin antibiotic targeting gram-positive and gram-negative bacteria. Is it not effective against many Bacteroides, Enterococci, and Haemophili species due to the resistance they have developed. Cefpirome sulfate with sodium carbonate is a mixture of cefpirome sulfate and anhydrous sodium carbonate and is commonly used for the stabilization of pH.
Cephalosporins are a type of β-lactam antibiotic consisting of a four-membered β-lactam ring bound to a six-membered dihydrothiazine ring. This two-ring system causes distortion of the β-lactam amide bond, resulting in decreased resonance stabilization and increased reactivity. β-lactams inhibit the formation of peptidoglycan cross-links within bacterial cell walls by targeting penicillin-binding proteins or PBPs. Consequently, the bacterial cell wall becomes weak and cytolysis occurs. Cephalosporins are less susceptible to β-lactamases than the penicillin β-lactam antibiotics.
Product Specifications
Cefpirome Sulfate with Sodium Carbonate
MOLECULAR BIOLOGY GRADE
Formula: C22H22N6O5S2 • H2SO4 and Na2CO3
MW: 612.66 g/mol (cefpirome sulfate) + 105.99 g/mol (sodium bicarbonate)
Storage/Handling: Store at 2-8 °C.
