Ceftizoxime Sodium

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Description

Ceftizoxime sodium is a third generation cephalosporin antibiotic effective against gram-negative and gram-positive bacteria. It is very soluble in aqueous solution.

Cephalosporins are a type of β-lactam antibiotic consisting of a four-membered β-lactam ring bound to a six-membered dihydrothiazine ring. This two-ring system causes distortion of the β-lactam amide bond, resulting in decreased resonance stabilization and increased reactivity. β-lactams inhibit the formation of peptidoglycan cross-links within bacterial cell walls by targeting penicillin-binding proteins or PBPs. Consequently, the bacterial cell wall becomes weak and cytolysis occurs. Cephalosporins are less susceptible to β-lactamases than the penicillin β-lactam antibiotics.


Product Specifications
Ceftizoxime Sodium

MOLECULAR BIOLOGY GRADE

Formula: C13H12N5NaO5S2

MW: 405.38 g/mol

Storage/Handling: Store at -20°C.

PubChem Chemical ID: 23663938

Ceftizoxime Sodium

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Catalog Number:
C-780-1
CAS Number:
68401-82-1
$157.00

For research use only. Not for food, drug, household, or cosmetic use.
Availability:
2-3 Weeks
Shipping:
$14.99 Ground shipping (In continental US only.)

    Description

    Ceftizoxime sodium is a third generation cephalosporin antibiotic effective against gram-negative and gram-positive bacteria. It is very soluble in aqueous solution.

    Cephalosporins are a type of β-lactam antibiotic consisting of a four-membered β-lactam ring bound to a six-membered dihydrothiazine ring. This two-ring system causes distortion of the β-lactam amide bond, resulting in decreased resonance stabilization and increased reactivity. β-lactams inhibit the formation of peptidoglycan cross-links within bacterial cell walls by targeting penicillin-binding proteins or PBPs. Consequently, the bacterial cell wall becomes weak and cytolysis occurs. Cephalosporins are less susceptible to β-lactamases than the penicillin β-lactam antibiotics.


    Product Specifications
    Ceftizoxime Sodium

    MOLECULAR BIOLOGY GRADE

    Formula: C13H12N5NaO5S2

    MW: 405.38 g/mol

    Storage/Handling: Store at -20°C.

    PubChem Chemical ID: 23663938

    Product Specifications

    Catalog ID: C-780
    CAS #: 68401-82-1
    MW: 405.38 g/mol
    Grade: MOLECULAR BIOLOGY GRADE
    Storage/handling: Store at -20°C.
    PubChem Chemical ID: 23663938
    IUPAC Name: sodium (6R,7R)-7-[[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
    InChI: InChI=1S/C13H13N5O5S2.Na/c1-23-17-7(5-4-25-13(14)15-5)9(19)16-8-10(20)18-6(12(21)22)2-3-24-11(8)18;/h2,4,8,11H,3H2,1H3,(H2,14,15)(H,16,19)(H,21,22);/q;+1/p-1/b17-7-;/t8-,11-;/m1./s1
    InChIKey: ADLFUPFRVXCDMO-LIGXYSTNSA-M
    SMILES: CON=C(C1=CSC(=N1)N)C(=O)NC2C3N(C2=O)C(=CCS3)C(=O)[O-].[Na+]

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