XTT Sodium Salt

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Description

XTT sodium salt is used in the XTT colormetric assay and assists in identifying metabolic activity within cells. In the XTT assay, the metabolic activity of cells reduces XTT sodium salt to an orange color formazan dye by dehydrogenase enzymes. Dye conversion will only occur in viable cells.

Since the reduction of XTT takes place by electron transport from outside the cell, the use of an intermediate electron acceptor, such as phenazine methosulfate (PMS) is usually required to perform a cell proliferation assay.

XTT sodium salt is similar to MTT (thiazolyl blue tetrazolium bromide); however, it offers advantages such as water solubility, low toxicity and higher sensitivity.


Product Specifications
XTT, Sodium Salt
Tetrazolium Reagent

HIGH PURITY GRADE

Formula: C22H16N7O13S2Na

MW: 673.52 g/mol

Storage/Handling: Store at 4°C.

PubChem Chemical ID: 14195569

XTT Sodium Salt

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Catalog Number:
X-200-100
CAS Number:
111072-31-2
$195.00

For research use only. Not for food, drug, household, or cosmetic use.
Availability:
In stock
Shipping:
$14.99 Ground shipping (In continental US only.)

    Description

    XTT sodium salt is used in the XTT colormetric assay and assists in identifying metabolic activity within cells. In the XTT assay, the metabolic activity of cells reduces XTT sodium salt to an orange color formazan dye by dehydrogenase enzymes. Dye conversion will only occur in viable cells.

    Since the reduction of XTT takes place by electron transport from outside the cell, the use of an intermediate electron acceptor, such as phenazine methosulfate (PMS) is usually required to perform a cell proliferation assay.

    XTT sodium salt is similar to MTT (thiazolyl blue tetrazolium bromide); however, it offers advantages such as water solubility, low toxicity and higher sensitivity.


    Product Specifications
    XTT, Sodium Salt
    Tetrazolium Reagent

    HIGH PURITY GRADE

    Formula: C22H16N7O13S2Na

    MW: 673.52 g/mol

    Storage/Handling: Store at 4°C.

    PubChem Chemical ID: 14195569

    Product Specifications

    Catalog ID: X-200
    CAS #: 111072-31-2
    Formula: C22H16N7O13S2Na
    MW: 673.52 g/mol
    Grade: HIGH PURITY GRADE
    Storage/handling: Store at 4°C.
    PubChem Chemical ID: 14195569
    IUPAC Name: sodium 4-methoxy-5-[3-(2-methoxy-4-nitro-5-sulfonatophenyl)-5-(phenylcarbamoyl)tetrazol-3-ium-2-yl]-2-nitrobenzenesulfonate
    InChI: InChI=1S/C22H17N7O13S2.Na/c1-41-17-8-15(28(31)32)19(43(35,36)37)10-13(17)26-24-21(22(30)23-12-6-4-3-5-7-12)25-27(26)14-11-20(44(38,39)40)16(29(33)34)9-18(14)42-2;/h3-11H,1-2H3,(H2-,23,30,35,36,37,38,39,40);/q;+1/p-1
    InChIKey: JACYMBNQPPWQML-UHFFFAOYSA-M
    SMILES: COC1=CC(=C(C=C1N2N=C(N=[N+]2C3=CC(=C(C=C3OC)[N+](=O)[O-])S(=O)(=O)[O-])C(=O)NC4=CC=CC=C4)S(=O)(=O)[O-])[N+](=O)[O-].[Na+]

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