IL36G (IL-36 gamma), Human (169 a.a.)

Product Description

GoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption!

Recombinant Human Interleukin-36γ
IL36G, IL36γ
Interleukin 1 Homolog 1 (IL1H1)
Interleukin 1-Related Protein 2 (IL1RP2)
Interleukin 1 Family, Member 9 (IL1F9)

Interleukin-36G (IL36G) is a pro-inflammatory cytokine that plays an important role in the pathophysiology of several diseases. IL36A, IL36B and IL36G; (formerly IL1F6, IL1F8, and IL1F9) are IL1 family members that signal through the IL1 receptor family members IL1Rrp2 (IL1RL2) and IL1RAcP. IL36B is secreted when transfected into 293-T cells and could constitute part of an independent signaling system analogous to that of IL1A and IL1B receptor agonist and interleukin-1 receptor type I (IL1R1). Furthermore, IL36G also can function as an agonist of NFκB activation through the orphan IL1-receptor-related protein 2. Recombinant human IL36G is synthesized as a protein that contains no signal sequence, no prosegment and no potential N-linked glycosylation site.There is a 53% amino acid homology between human and mouse IL36G. IL36G also has a 25-55% amino acid homology with IL36G and IL1RN, IL1B, IL36RN, IL36A, IL37, IL36B and IL1F10.

Sterile Filtered White Lyophilized Powder. Purified and tested for use in cell culture.

Source: Escherichia coli

MW: ~18.7 kDa (169 amino acids)

Purity: >95% by SDS-PAGE and HPLC analyses.

Storage/Handling: Store desiccated at -20°C.

NOT FOR HUMAN USE!

HGNC: 15741

Additional resources for this protein may be found at:
OMIM

Product Specifications

Catalog ID 1110-36E
MW ~18.7 kDa
Storage/Handling Store desiccated at -20°C.

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