IL33, Rat

Product Description

GoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption!

Recombinant Rat Interleukin-33
IL33
Interleukin 33
IL1F11
Nuclear Factor from High Endothelial Venules (NF-HEV)
Chromosome 9 Open Reading Frame 26 (C9ORF26)

Interleukin-33 (IL33), also known as NF-HEV and DVS 27, is a cytokine belonging to the IL1 superfamily. IL33 is a pro-inflammatory protein that may regulate gene transcription and induce helper T-cells, mast cells, eosinophils and basophils to produce type 2 cytokines. The induction of type 2 cytokines by IL33 in vivo is believed to induce the severe pathological changes observed in mucosal organs following administration of IL33. IL33 is constitutively expressed in smooth muscle and airway epithelia, and it binds to a high-affinity receptor family member ST2. In vivo administration of mature IL33 promotes increased production of IL5, IL13, IgE and IgA, as well as splenomegaly and inflammatory infiltration of mucosal tissues.

Sterile Filtered White Lyophilized Powder. Purified and tested for use in cell culture.

Source: Escherichia coli

MW: ~17.4 kDa (156 amino acids)

Purity: >95% by SDS-PAGE and HPLC analyses.

Storage/Handling: Store desiccated at -20°C.

NOT FOR HUMAN USE!

Rat Genome Database ID: 1311155

Cross-species Homology


Percent Similarity:

HuIL33 MuIL33 RtIL33
HuIL33 *** 57.5 59.4
MuIL33 *** *** 89.9
RtIL33 *** *** ***

Additional resources for this protein may be found at:
OMIM

Product Specifications

Catalog ID 1510-33
MW ~17.4 kDa
Storage/Handling Store desiccated at -20°C.

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