Description
Recombinant Human PTH (1-84) contains the complete 84 amino acid sequence of mature human parathyroid hormone. PTH regulates calcium and phosphate homeostasis through receptor-mediated signaling in tissues including bone and kidney and contributes to the control of osteoblast activity, bone remodeling, and mineral metabolism.
As the full-length form of PTH, this recombinant protein is particularly useful for studies requiring the complete native hormone sequence rather than a shorter N-terminal fragment. It can be used to investigate PTH1R signaling, cAMP production, osteoblast responses, calcium regulation, and differences between intact PTH and truncated PTH peptides.
GoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption!
Sterile Filtered White lyophilized powder. Purified and tested for use in cell culture.
Recombinant Human Parathyroid Hormone (PTH)
Parathyrin
Parathormone
Parathyroid Hormone 1 (PTH1)
Source: Escherichia coli
MW: ~9.4 kDa (84 amino acids)
Purity: >97% by SDS-PAGE and HPLC analyses
Biological Activity: Fully biologically active when compared to standard. The ED50 as determined by its ability to induce cAMP accumulation in murine MC3T3E1 cells is less than 50 ng/ml, corresponding to a specific activity of >2.0×104 IU/mg.
Storage/Handling: Store desiccated at -20°C.
HGNC: 9606
NOT FOR HUMAN USE!
Additional resources for this protein may be found at:
OMIM
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