Description
Aztreonam is a monobactam β-lactam antibiotic whose structure contains only a single ring. Its unique ring structure makes it resistant to β-lactamases. Aztreonam is effective against gram-negative bacteria and is an economical antibiotic commonly used in plant tissue culture applications and against P. aeruginosa.
β-lactams inhibit the formation of peptidoglycan cross-links within bacterial cell walls by targeting penicillin-binding proteins or PBPs. Consequently, the bacterial cell wall becomes weak and cytolysis occurs. Resistance to β-lactam antibiotics occurs in the presence of cells containing plasmid encoded extended spectrum β-lactamases or ESBLs.
Product Specifications
Aztreonam
MOLECULAR BIOLOGY GRADE
Formula: C13H17N5O8S2
MW: 435.43 g/mol
Storage/Handling: Store at 4°C.
Aztreonam is soluble in DMF and DMSO and is insoluble in water.
PubChem Chemical ID: 5742832
