Description
Rapamycin is a macrolide antibiotic isolated from Streptomyces hygroscopicus. It has been shown to display anticancer activity such as induction of apoptosis and inhibition of angiogenesis and proliferation in tumor cell lines. Rapamycin is also an immunosuppressant and FRAP inhibitor and inhibits lymphokine-induced cell proliferation.
Rapamycin works by forming a complex with FKBP12 and binding mTOR (mechanistic target of rapamycin), causing it to be inhibited.
Product Specifications
Sirolimus
Rapamune
Rapamycin
Formula:C 51H79NO13
MW:914.17 g/mol
Storage/Handling:This product is soluble in DMSO or Ethanol.
PubChem Chemical ID:5284616