AEBSF

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Description

AEBSF is an irreversible serine protease inhibitor. AEBSF has been shown to inhibit trypsin, chymotrypsin, plasmin, kallikrein and thrombin. It inhibits the active site of the enzyme through acylation. As an alternative to PMSF and DFP, AEBSF offers lower toxicity, improved solubility in water and improved stability in aqueous solutions. AEBSF has been used in cell culture in concentrations of up to 0.25mM. Aqueous solutions are stable between pH 5-6; limited stability above pH 7.5.

Attention Canadian and Mexican customers: This product is a hazardous and can only ship via Air.

Applications

  • Serine Protease inhibitor
  • SREBP protein activation
  • PMSF/DFP alternative

Storage and Handling

Store at -20°C. Protect from light.

Working Concentration

Make stock solutions at 100mM. Aliquot and store at -20°C for up to 2 months.
AEBSF working concentrations are usually between 0.1-1.0mM and should be made daily.

AEBSF

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Catalog Number:
A-540-500
CAS Number:
30827-99-7
$72.00

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    Description

    AEBSF is an irreversible serine protease inhibitor. AEBSF has been shown to inhibit trypsin, chymotrypsin, plasmin, kallikrein and thrombin. It inhibits the active site of the enzyme through acylation. As an alternative to PMSF and DFP, AEBSF offers lower toxicity, improved solubility in water and improved stability in aqueous solutions. AEBSF has been used in cell culture in concentrations of up to 0.25mM. Aqueous solutions are stable between pH 5-6; limited stability above pH 7.5.

    Attention Canadian and Mexican customers: This product is a hazardous and can only ship via Air.

    Applications

    • Serine Protease inhibitor
    • SREBP protein activation
    • PMSF/DFP alternative

    Storage and Handling

    Store at -20°C. Protect from light.

    Working Concentration

    Make stock solutions at 100mM. Aliquot and store at -20°C for up to 2 months.
    AEBSF working concentrations are usually between 0.1-1.0mM and should be made daily.

    Product Specifications

    Catalog ID: A-540
    CAS #: 30827-99-7
    Formula: C8H10FNO2S · HCl
    MW: 239.69 g/mol
    Grade: MOLECULAR BIOLOGY GRADE
    Storage/handling: Store at -20°C. Protect from light.
    PubChem Chemical ID: 186136

    CITATIONS

    Featured Articles

    • 3 Key Differences Between AEBSF and PMSF Protease Inhibitors

      3 Key Differences Between AEBSF and PMSF Protease Inhibitors

      AEBSF and PMSF are both irreversible protease inhibitors of serine proteases. With them both inhibiting serine proteases, you may be curious about their differences. What...

      Read more

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