Description
Amikacin hydrate is a broad-spectrum aminoglycoside antibiotic derived from kanamycin A. It is effective against gram-negative bacteria such as Pseudomonas aeruginosa and a variety of enteric species. It is also effective against Mycobacterium tuberculosis. Amikacin hydrate is freely soluble in aqueous solution.
Aminoglycoside antibiotics are composed of amino groups attached to glycosides. They bind the 30s ribosomal subunit, causing misreading of the mRNA sequence and inhibition of translocation. Consequently, protein synthesis is inhibited.
Samples of microbes grown in the presence of a 30 μg amikacin disc with a zone of inhibition of <14 mm in diameter are considered resistant. Intermediate resistance zones of inhibition are typically 15 mm-16 mm in diameter.
Product Specifications
Amikacin Hydrate
MOLECULAR BIOLOGY GRADE
Formula: C22H43N5O13 ∙ XH2O
MW: 585.60 g/mol (anhydrous)
Storage/Handling: Store desiccated at 2-8°C.
PubChem Chemical ID: 37768
Powered by Bioz