Description
Ampicillin/sulbactam (2:1) is a broad-spectrum combination of a β-lactam antibiotic with a β-lactamase inhibitor. It is used for in vitro susceptibility tests in microbiology, pharmacokinetics and pharmacodynamics studies.
Ampicillin binds to the active site of penicillin binding proteins (PBP), preventing peptidoglycan cross-link formation of the bacterial cell wall. Inhibition of PBPs weakens the bacterial cell wall and leads to cell lysis. Sulbactam irreversibly inhibits β-lactamase enzymes generated by bacteria, preserving ampicillin activity and enhancing potency.
Product Specifications
Ampicillin/sulbactam (2:1)
Unacyne
Sulbactam-ampicillin mixt.
Formula: C25H29N3Na2O9S2
MW: 625.62 g/mol
Storage/Handling: Store desiccated at -20°C.
PubChem Chemical ID: 71300936
