Description
Bleomycin Sulfate is an anti-cancer agent isolated from Streptomyces verticillus. Bleomycin is a mixture of bleomycin A2 and bleomycin B2, in an approximately 2:1 ratio, respectively. However, the ratio varies by lot number.
Bleomycin is used against Hodgkin’s lymphoma. Its mechanism is not well understood; however, it is though that bleomycin chelates metallic ions causing a decrease in enzyme stability. The enzymes react with oxygen and produce free radicals, ultimately causing single-stranded breaks in deoxyribose sugars of DNA.
Product Specifications
Bleomycin Sulfate, USP Grade
Formula: C55H84N17O21S3 ∙ H2SO4
MW: 1,512.62 g/mol
Storage/Handling: Store desiccated at 4°C.
Strongly hygroscopic.
PubChem Chemical ID: 46930981
Air shipments may require special packaging and a small additional box charge.
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