Description
GoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption!
Recombinant Human Chemokine (C-C motif) Ligand 21 (CCL21)
T Cell Activation 4 (TCA4, TCA-4)
Small Inducible Cytokine Subfamily A Member 21 (SCYA21)
Secondary Lymphoid Tissue Chemokine (SLC)
Exodus 2
CCL21 is a chemokine containing six conserved cysteine residues, two of which are adjacent. It is expressed in high endothelial venules of lymph nodes, as well as tonsils, breast stromal cells, and a variety of other cells. Expression of CCL21 is inhibited by IFNG. It is chemotactic for peripheral blood lymphocytes and plays a major role in initiation and expansion of adaptive immune responses, as well as development of local lymphoid tissue. CCL21 is a ligand for CCR7, as well as CXCR3 and the virorecptor M3.
Sterile Filtered White lyophilized powder. Purified and tested for use in cell culture.
Source: Escherichia coli
MW: ~12.2 kDa (111 amino acids)
Purity: >97% by SDS-PAGE and HPLC analyses
Biological Activity: Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human lymphocytes is in a concentration of 10-100 ng/ml.
Storage/Handling: Store desiccated at -20°C.
HGNC: 10620
NOT FOR HUMAN USE!
Additional resources for this protein may be found at:
OMIM
