Cefepime HCl

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Description

Cefepime HCl is more soluble compared to the pure Cefepime. Both forms have similar potencies and both are suitable for microbiology use. However, Cefepime HCl can be easier to work with because of its higher aqueous solubility.

Cefepime HCl is a 4th generation cephalosporin antibiotic that is effective against gram-negative and gram-positive bacteria. It is resistant to a variety of β-lactamases, and is effective against some naturally resistant bacterial species such as Pseudomonas aeruginosa, Staphylococcus aureus, and Streptococcus pneumoniae. 

Cephalosporins are a type of β-lactam antibiotic consisting of a four-membered β-lactam ring bound to a six-membered dihydrothiazine ring. This two-ring system causes distortion of the β-lactam amide bond, resulting in decreased resonance stabilization and increased reactivity. β-lactams inhibit the formation of peptidoglycan cross-links within bacterial cell walls by targeting penicillin-binding proteins or PBPs. Consequently, the bacterial cell wall becomes weak and cytolysis occurs. Cephalosporins are less susceptible to β-lactamases than the penicillin β-lactam antibiotics.


Product Specifications
Cefepime HCl
Cefepime Hydrochloride

MOLECULAR BIOLOGY GRADE

Formula: C19H25ClN6O5S2 ∙ HCl ∙ H2O

MW: 571.50 g/mol

Storage/Handling: Store at - 20 °C. Product is light sensitive.

PubChem Chemical ID: 9571075

Cefepime HCl

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Catalog Number:
C-611-100
CAS Number:
123171-59-5
$343.00

For research use only. Not for food, drug, household, or cosmetic use.
Availability:
2-3 Weeks
Shipping:
$14.99 Ground shipping (In continental US only.)

    Description

    Cefepime HCl is more soluble compared to the pure Cefepime. Both forms have similar potencies and both are suitable for microbiology use. However, Cefepime HCl can be easier to work with because of its higher aqueous solubility.

    Cefepime HCl is a 4th generation cephalosporin antibiotic that is effective against gram-negative and gram-positive bacteria. It is resistant to a variety of β-lactamases, and is effective against some naturally resistant bacterial species such as Pseudomonas aeruginosa, Staphylococcus aureus, and Streptococcus pneumoniae. 

    Cephalosporins are a type of β-lactam antibiotic consisting of a four-membered β-lactam ring bound to a six-membered dihydrothiazine ring. This two-ring system causes distortion of the β-lactam amide bond, resulting in decreased resonance stabilization and increased reactivity. β-lactams inhibit the formation of peptidoglycan cross-links within bacterial cell walls by targeting penicillin-binding proteins or PBPs. Consequently, the bacterial cell wall becomes weak and cytolysis occurs. Cephalosporins are less susceptible to β-lactamases than the penicillin β-lactam antibiotics.


    Product Specifications
    Cefepime HCl
    Cefepime Hydrochloride

    MOLECULAR BIOLOGY GRADE

    Formula: C19H25ClN6O5S2 ∙ HCl ∙ H2O

    MW: 571.50 g/mol

    Storage/Handling: Store at - 20 °C. Product is light sensitive.

    PubChem Chemical ID: 9571075

    Product Specifications

    Catalog ID: C-611
    CAS #: 123171-59-5
    MW: 571.50 g/mol
    Grade: MOLECULAR BIOLOGY GRADE
    Storage/handling: Store at -20°C.
    PubChem Chemical ID: 9571075
    IUPAC Name: (6R,7R)-7-[[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-3-[(1-methylpyrrolidin-1-ium-1-yl)methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;chloride;hydrate;hydrochloride
    InChI: InChI=1S/C19H24N6O5S2.2ClH.H2O/c1-25(5-3-4-6-25)7-10-8-31-17-13(16(27)24(17)14(10)18(28)29)22-15(26)12(23-30-2)11-9-32-19(20)21-11;;;/h9,13,17H,3-8H2,1-2H3,(H3-,20,21,22,26,28,29);2*1H;1H2/b23-12-;;;/t13-,17-;;;/m1.../s1
    InChIKey: LRAJHPGSGBRUJN-OMIVUECESA-N
    SMILES: C[N+]1(CCCC1)CC2=C(N3C(C(C3=O)NC(=O)C(=NOC)C4=CSC(=N4)N)SC2)C(=O)O.O.Cl.[Cl-]

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