Description
Cefozopran is a fourth generation cephalosporin antibiotic effective against a variety of gram-negative and gram-positive organisms, including Pseudomonas aeruginosa. It is effective against MRSA when combined with antibiotics such as vancomycin and teicoplanin. Cefozopran HCl is soluble in DMSO and water.
Cephalosporins are a type of β-lactam antibiotic consisting of a four-membered β-lactam ring bound to a six-membered dihydrothiazine ring. This two-ring system causes distortion of the β-lactam amide bond, resulting in decreased resonance stabilization and increased reactivity. β-lactams inhibit the formation of peptidoglycan cross-links within bacterial cell walls by targeting penicillin-binding proteins or PBPs. Consequently, the bacterial cell wall becomes weak and cytolysis occurs. Cephalosporins are less susceptible to β-lactamases than the penicillin β-lactam antibiotics.
Product Specifications
Cefozopran HCl
Cefozopran Hydrochloride
MOLECULAR BIOLOGY GRADE
Formula: C19H17N9O5S2 ∙ HCl
MW: 551.99 g/mol
Storage/Handling: Store at 2-8 °C.
PubChem Chem ID: 9690120
