Cefpodoxime, Free acid

Description

Cefpodoxime is a third generation cephalosporin antibiotic. It targets gram-positive and gram-negative bacteria, especially those responsible for otitis media and pharyngitis.

Cephalosporins are a type of β-lactam antibiotic consisting of a four-membered β-lactam ring bound to a six-membered dihydrothiazine ring. This two-ring system causes distortion of the β-lactam amide bond, resulting in decreased resonance stabilization and increased reactivity. β-lactams inhibit the formation of peptidoglycan cross-links within bacterial cell walls by targeting penicillin-binding proteins or PBPs. Consequently, the bacterial cell wall becomes weak and cytolysis occurs. Cephalosporins are less susceptible to β-lactamases than the penicillin β-lactam antibiotics.


Product Specifications
Cefpodoxime, Free Acid

MOLECULAR BIOLOGY GRADE

Formula: C15H17N5O6S2

MW: 427.46 g/mol

Storage/Handling: Store at -20°C.
Product is light sensitive. Soluble in DMSO

PubChem Chemical ID: 6335986

Cefpodoxime, Free acid

View Sizes & Pricing

Catalog Number:
C-712-100
CAS Number:
80210-62-4
$289.00

For research use only. Not for food, drug, household, or cosmetic use.
Availability:
2-3 Weeks
Shipping:
$14.99 Ground shipping (In continental US only.)

    Description

    Cefpodoxime is a third generation cephalosporin antibiotic. It targets gram-positive and gram-negative bacteria, especially those responsible for otitis media and pharyngitis.

    Cephalosporins are a type of β-lactam antibiotic consisting of a four-membered β-lactam ring bound to a six-membered dihydrothiazine ring. This two-ring system causes distortion of the β-lactam amide bond, resulting in decreased resonance stabilization and increased reactivity. β-lactams inhibit the formation of peptidoglycan cross-links within bacterial cell walls by targeting penicillin-binding proteins or PBPs. Consequently, the bacterial cell wall becomes weak and cytolysis occurs. Cephalosporins are less susceptible to β-lactamases than the penicillin β-lactam antibiotics.


    Product Specifications
    Cefpodoxime, Free Acid

    MOLECULAR BIOLOGY GRADE

    Formula: C15H17N5O6S2

    MW: 427.46 g/mol

    Storage/Handling: Store at -20°C.
    Product is light sensitive. Soluble in DMSO

    PubChem Chemical ID: 6335986

    Product Specifications

    Catalog ID: C-712
    CAS #: 80210-62-4
    MW: 427.46 g/mol
    Grade: MOLECULAR BIOLOGY GRADE
    Storage/handling: Store at -20°C.
    PubChem Chemical ID: 6335986
    IUPAC Name: (6R,7R)-7-[[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-3-(methoxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
    InChI: InChI=1S/C15H17N5O6S2/c1-25-3-6-4-27-13-9(12(22)20(13)10(6)14(23)24)18-11(21)8(19-26-2)7-5-28-15(16)17-7/h5,9,13H,3-4H2,1-2H3,(H2,16,17)(H,18,21)(H,23,24)/b19-8-/t9-,13-/m1/s1
    InChIKey: WYUSVOMTXWRGEK-HBWVYFAYSA-N
    SMILES: COCC1=C(N2C(C(C2=O)NC(=O)C(=NOC)C3=CSC(=N3)N)SC1)C(=O)O

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