Description
Cefteram pivoxil is a semi-synthetic third generation cephalosporin antibacterial that is a prodrug ester of cefteram. It has been seen to express greater bactericidal predominantly against gram-negative bacteria. Cefteram pivoxil has also induced IgE antibody immune responses during in vivo immunology studies.
Cephalosporins are a type of β-lactam antibiotic consisting of a four-membered β-lactam ring bound to a six-membered dihydrothiazine ring. This two-ring system causes distortion of the β-lactam amide bond, resulting in decreased resonance stabilization and increased reactivity. β-lactams inhibit the formation of peptidoglycan cross-links within bacterial cell walls by targeting penicillin-binding proteins or PBPs. Consequently, the bacterial cell wall becomes weak and cytolysis occurs. Cephalosporins are less susceptible to β-lactamases than the penicillin β-lactam antibiotics.
Product Specifications
Cefteram pivoxil
Formula: C22H27N9O7S2
MW: 593.63 g/mol
Storage/Handling: Store at -20°C.
PubChem Chemical ID: 5362114
