Ceftibuten

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Description

Ceftibuten is a third generation cephalosporin antibiotic targeting a broad-spectrum of gram-positive and gram-negative bacteria. Ceftibuten is freely soluble in aqueous solution.

Cephalosporins are a type of β-lactam antibiotic consisting of a four-membered β-lactam ring bound to a six-membered dihydrothiazine ring. This two-ring system causes distortion of the β-lactam amide bond, resulting in decreased resonance stabilization and increased reactivity. β-lactams inhibit the formation of peptidoglycan cross-links within bacterial cell walls by targeting penicillin-binding proteins or PBPs. Consequently, the bacterial cell wall becomes weak and cytolysis occurs. Cephalosporins are less susceptible to β-lactamases than the penicillin β-lactam antibiotics.


Product Specifications
Ceftibuten

MOLECULAR BIOLOGY GRADE

Formula: C15H14N4O6S2

MW: 410.42 g/mol

Storage/Handling: Store at 2-8°C. This product is soluble in DMSO.

PubChem Chemical ID: 5282242

Ceftibuten

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Catalog Number:
C-760-10
CAS Number:
97519-39-6
$70.00

For research use only. Not for food, drug, household, or cosmetic use.
Availability:
2-3 Weeks
Shipping:
$14.99 Ground shipping (In continental US only.)

    Description

    Ceftibuten is a third generation cephalosporin antibiotic targeting a broad-spectrum of gram-positive and gram-negative bacteria. Ceftibuten is freely soluble in aqueous solution.

    Cephalosporins are a type of β-lactam antibiotic consisting of a four-membered β-lactam ring bound to a six-membered dihydrothiazine ring. This two-ring system causes distortion of the β-lactam amide bond, resulting in decreased resonance stabilization and increased reactivity. β-lactams inhibit the formation of peptidoglycan cross-links within bacterial cell walls by targeting penicillin-binding proteins or PBPs. Consequently, the bacterial cell wall becomes weak and cytolysis occurs. Cephalosporins are less susceptible to β-lactamases than the penicillin β-lactam antibiotics.


    Product Specifications
    Ceftibuten

    MOLECULAR BIOLOGY GRADE

    Formula: C15H14N4O6S2

    MW: 410.42 g/mol

    Storage/Handling: Store at 2-8°C. This product is soluble in DMSO.

    PubChem Chemical ID: 5282242

    Product Specifications

    Catalog ID: C-760
    CAS #: 97519-39-6
    MW: 410.42 g/mol
    Grade: MOLECULAR BIOLOGY GRADE
    Storage/handling: Store at 4°C.
    PubChem Chemical ID: 5282242
    IUPAC Name: (6R,7R)-7-[[(Z)-2-(2-amino-1,3-thiazol-4-yl)-4-carboxybut-2-enoyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
    InChI: InChI=1S/C15H14N4O6S2/c16-15-17-7(5-27-15)6(1-2-9(20)21)11(22)18-10-12(23)19-8(14(24)25)3-4-26-13(10)19/h1,3,5,10,13H,2,4H2,(H2,16,17)(H,18,22)(H,20,21)(H,24,25)/b6-1-/t10-,13-/m1/s1
    InChIKey: UNJFKXSSGBWRBZ-BJCIPQKHSA-N
    SMILES: C1C=C(N2C(S1)C(C2=O)NC(=O)C(=CCC(=O)O)C3=CSC(=N3)N)C(=O)O

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