Ceftiofur Sodium

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Description

Ceftiofur sodium is a third generation cephalosporin antibiotic effective against gram-positive and gram-negative bacteria. Although ceftiofur is resistant to β-lactamase degradation, there are several strains of E. coli known to be unaffected by this antibiotic. It is soluble in aqueous solution.

Cephalosporins are a type of β-lactam antibiotic consisting of a four-membered β-lactam ring bound to a six-membered dihydrothiazine ring. This two-ring system causes distortion of the β-lactam amide bond, resulting in decreased resonance stabilization and increased reactivity. β-lactams inhibit the formation of peptidoglycan cross-links within bacterial cell walls by targeting penicillin-binding proteins or PBPs. Consequently, the bacterial cell wall becomes weak and cytolysis occurs. Cephalosporins are less susceptible to β-lactamases than the penicillin β-lactam antibiotics.


Product Specifications
Ceftiofur Sodium

MOLECULAR BIOLOGY GRADE

Formula: C19H16N5NaO7S3

MW: 545.54 g/mol

Storage/Handling: Store at 2-8°C.

PubChem Chemical ID: 23671563

Ceftiofur Sodium

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Catalog Number:
C-770-1
CAS Number:
104010-37-9
$117.00

For research use only. Not for food, drug, household, or cosmetic use.
Availability:
2-3 Weeks
Shipping:
$14.99 Ground shipping (In continental US only.)

    Description

    Ceftiofur sodium is a third generation cephalosporin antibiotic effective against gram-positive and gram-negative bacteria. Although ceftiofur is resistant to β-lactamase degradation, there are several strains of E. coli known to be unaffected by this antibiotic. It is soluble in aqueous solution.

    Cephalosporins are a type of β-lactam antibiotic consisting of a four-membered β-lactam ring bound to a six-membered dihydrothiazine ring. This two-ring system causes distortion of the β-lactam amide bond, resulting in decreased resonance stabilization and increased reactivity. β-lactams inhibit the formation of peptidoglycan cross-links within bacterial cell walls by targeting penicillin-binding proteins or PBPs. Consequently, the bacterial cell wall becomes weak and cytolysis occurs. Cephalosporins are less susceptible to β-lactamases than the penicillin β-lactam antibiotics.


    Product Specifications
    Ceftiofur Sodium

    MOLECULAR BIOLOGY GRADE

    Formula: C19H16N5NaO7S3

    MW: 545.54 g/mol

    Storage/Handling: Store at 2-8°C.

    PubChem Chemical ID: 23671563

    Product Specifications

    Catalog ID: C-770
    CAS #: 104010-37-9
    MW: 545.54 g/mol
    Grade: MOLECULAR BIOLOGY GRADE
    Storage/handling: Store at 4°C.
    PubChem Chemical ID: 23671563
    IUPAC Name: sodium (6R,7R)-7-[[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-3-(furan-2-carbonylsulfanylmethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
    InChI: InChI=1S/C19H17N5O7S3.Na/c1-30-23-11(9-7-34-19(20)21-9)14(25)22-12-15(26)24-13(17(27)28)8(5-32-16(12)24)6-33-18(29)10-3-2-4-31-10;/h2-4,7,12,16H,5-6H2,1H3,(H2,20,21)(H,22,25)(H,27,28);/q;+1/p-1/b23-11-;/t12-,16-;/m1./s1
    InChIKey: RFLHUYUQCKHUKS-JUODUXDSSA-M
    SMILES: CON=C(C1=CSC(=N1)N)C(=O)NC2C3N(C2=O)C(=C(CS3)CSC(=O)C4=CC=CO4)C(=O)[O-].[Na+]

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