Description
Ceftizoxime sodium is a third generation cephalosporin antibiotic effective against gram-negative and gram-positive bacteria. It is very soluble in aqueous solution.
Cephalosporins are a type of β-lactam antibiotic consisting of a four-membered β-lactam ring bound to a six-membered dihydrothiazine ring. This two-ring system causes distortion of the β-lactam amide bond, resulting in decreased resonance stabilization and increased reactivity. β-lactams inhibit the formation of peptidoglycan cross-links within bacterial cell walls by targeting penicillin-binding proteins or PBPs. Consequently, the bacterial cell wall becomes weak and cytolysis occurs. Cephalosporins are less susceptible to β-lactamases than the penicillin β-lactam antibiotics.
Product Specifications
Ceftizoxime Sodium
MOLECULAR BIOLOGY GRADE
Formula: C13H12N5NaO5S2
MW: 405.38 g/mol
Storage/Handling: Store at -20°C.
PubChem Chemical ID: 23663938
