CHAPS

Request Lot Specific COA

Citation Search Tool

Description

CHAPS , also known as ((3-cholamidopropyl)dimethylammonio)-1-propanesulfonate, is a zwitterionic surfactant primarily used to solubilize membrane proteins and other macromolecules.

Oftentimes, mild detergents are used in cell lysis applications by interfering with membrane interactions.

When in salt, CHAPS tends to behave as a weakly charged cation; however, in water or buffer, it behaves as a nonionic surfactant.

Studies have shown that when CHAPs is combined with Triton X-100 and sarkosyl, binding efficiency of GST and GST fusion proteins to glutathione (GSH) Sepharose is significantly increased.

It can be removed from gels and protein solutions by dialysis across a membrane.


Product Specifications
CHAPS
3-((3-cholamidopropyl)dimethylammonium)-1-propanesulfonate

ULTRA PURITY GRADE

Formula: C32H58N2O7S

MW: 614.88 g/mol

Storage/Handling: Store at 4°C.

PubChem Chemical ID: 107670.

CHAPS

View Sizes & Pricing

Catalog Number:
C-080-1
CAS Number:
75621-03-3
$38.00

Availability:
In Stock
Shipping:
Shipping calculated at checkout

    Description

    CHAPS , also known as ((3-cholamidopropyl)dimethylammonio)-1-propanesulfonate, is a zwitterionic surfactant primarily used to solubilize membrane proteins and other macromolecules.

    Oftentimes, mild detergents are used in cell lysis applications by interfering with membrane interactions.

    When in salt, CHAPS tends to behave as a weakly charged cation; however, in water or buffer, it behaves as a nonionic surfactant.

    Studies have shown that when CHAPs is combined with Triton X-100 and sarkosyl, binding efficiency of GST and GST fusion proteins to glutathione (GSH) Sepharose is significantly increased.

    It can be removed from gels and protein solutions by dialysis across a membrane.


    Product Specifications
    CHAPS
    3-((3-cholamidopropyl)dimethylammonium)-1-propanesulfonate

    ULTRA PURITY GRADE

    Formula: C32H58N2O7S

    MW: 614.88 g/mol

    Storage/Handling: Store at 4°C.

    PubChem Chemical ID: 107670.

    Product Specifications

    Catalog ID: C-080
    CAS #: 75621-03-3
    MW: 614.88 g/mol
    Grade: ULTRA PURITY GRADE
    Storage/handling: Store at 4°C.

    CITATIONS

    Featured Articles

    • 12 Useful Detergents for Your Experiments

      12 Useful Detergents for Your Experiments

      You might be designing a cell lysis experiment to extract your target protein in its native form, or you have isolated cell membranes from which...

      Read more

    Login

    Forgot your password?

    Don't have an account yet?
    Create account