Description
Chlortetracycline, isolated from Streptomyces aureofaciens, was the first tetracycline antibiotic discovered. It has shown the most efficacy against gram-positive organisms, but is also effective on a variety of gram-negative bacteria. Resistance to chlortetracycline arises from a loss of cell wall permeability.
Tetracyclines are antibiotics made up of a four-ring system. They bind the 30s ribosomal subunit, preventing the aminoacyl-tRNA from attaching to the A site. Consequently, protein synthesis is inhibited.
Product Specifications
Chlortetracycline HCl, USP Grade
7-Chlorotetracycline, USP Grade
Formula: C22H23ClN2O8 ∙ HCl
MW: 515.34 g/mol
Storage/Handling: Store at -20°C. Protect from light.
PubChem Chemical ID: 54684459
