Colchicine

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Description

Colchicine is an alkaloid isolated from Colchicum autumnale and other Colchica species. It is an antimitotic agent useful against various cancer cell lines. Colchicine disrupts microtubules and can be used to induce tetraploidy in plant cells. It is an activator of the JNK/SAPK signaling pathway and used to select for cells containing MDCK (NBL-2) resistance. Colchicine’s antimitotic properties are more effective against cancer cells due to their increased mitotic rate compared to that of healthy cells. Colchicine is useful in cell division studies.

Product Specifications
Colchicine

MOLECULAR BIOLOGY GRADE

Formula: C22H25NO6

MW: 399.44 g/mol

Storage/Handling: Store at 2-8 °C.
This product is light sensitive.

PubChem Chemical ID: 6167

Air shipments may require special packaging and a small additional box charge.

Colchicine

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Catalog Number:
C-910-500
CAS Number:
64-86-8
$82.00

For research use only. Not for food, drug, household, or cosmetic use.
Availability:
2-3 Weeks
Shipping:
$14.99 Ground shipping (In continental US only.)

    Description

    Colchicine is an alkaloid isolated from Colchicum autumnale and other Colchica species. It is an antimitotic agent useful against various cancer cell lines. Colchicine disrupts microtubules and can be used to induce tetraploidy in plant cells. It is an activator of the JNK/SAPK signaling pathway and used to select for cells containing MDCK (NBL-2) resistance. Colchicine’s antimitotic properties are more effective against cancer cells due to their increased mitotic rate compared to that of healthy cells. Colchicine is useful in cell division studies.

    Product Specifications
    Colchicine

    MOLECULAR BIOLOGY GRADE

    Formula: C22H25NO6

    MW: 399.44 g/mol

    Storage/Handling: Store at 2-8 °C.
    This product is light sensitive.

    PubChem Chemical ID: 6167

    Air shipments may require special packaging and a small additional box charge.

    Product Specifications

    Catalog ID: C-910
    CAS #: 64-86-8
    Formula: C22H25NO6
    MW: 399.44 g/mol
    Grade: MOLECULAR BIOLOGY GRADE
    Storage/handling: Store at 4°C.
    UN number: 1544
    group number: I
    item class: 6.1
    PubChem Chemical ID: 6167
    IUPAC Name: N-[(7S)-1,2,3,10-tetramethoxy-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl]acetamide
    InChI: InChI=1S/C22H25NO6/c1-12(24)23-16-8-6-13-10-19(27-3)21(28-4)22(29-5)20(13)14-7-9-18(26-2)17(25)11-15(14)16/h7,9-11,16H,6,8H2,1-5H3,(H,23,24)/t16-/m0/s1
    InChIKey: IAKHMKGGTNLKSZ-INIZCTEOSA-N
    SMILES: CC(=O)NC1CCC2=CC(=C(C(=C2C3=CC=C(C(=O)C=C13)OC)OC)OC)OC

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