Description
 GoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption! 
  Recombinant  Human Chemokine (C-X-C motif) Ligand 2 
 Melanoma  Growth Stimulating Activity, Beta (MGSB, MGSA-b) 
 Macrophage  Inflammatory Protein 2 (MIP2, MIP2-alpha) 
 Growth Related  Oncogene 2 (GRO2, GRO-beta) 
 Cytokine  Induced Neutrophil Chemoattractant 2, Alpha (CINC2-alpha) 
 Small  Inducible Cytokine Subfamily B Member 2 (SCYB2) 
  CXCL2 is an ELR type of CXC chemokine. It is secreted by monocytes and macrophages and expressed in a variety of other cells. CXCL2 participates in chemotaxis of polymorphonuclear leukocytes and hematopoietic stem cells. It plays a role in would healing, angiogenesis, tumorigenesis, and pathogenesis of airway remodeling in asthma. CXCL2 exhibits antimicrobial activity against E. coli and S. aureus. CXCR2 is the receptor that CXCL2 binds. The amino acid sequence of CXCL2 is significantly homologous to that of CXCL1. 
  Sterile Filtered White lyophilized powder. Purified and tested for use in cell culture. 
  Source: Escherichia coli 
  MW: ~7.9 kDa (73 amino  acids) 
  Purity: >97% by SDS-PAGE  and HPLC analyses 
  Biological Activity: Fully biologically  active when compared to standard. The biological activity determined by a chemotaxis bioassay using human CXCR2 transfected human 293 cells is in a concentration  range of 10-100 ng/ml. 
  Storage/Handling: Store desiccated at  -20°C. 
  HGNC: 4603 
  NOT FOR HUMAN USE! 
  Additional resources for this protein may be found at:
 OMIM