Description
Dabrafenib is a compound used as a serine/threonine-protein kinase B-Raf inhibitor for oncology research. It competitively inhibits V600E BRAF gene mutations which are characteristic in melanoma cancers. Inhibition of B-Raf proteins, by dabrafenib, interrupts mitogen-activated protein kinase/extracellular signal regulated kinase (MAPK/ERK) pathways, which regulate cell growth.This action halts cell proliferative activity and engages apoptosis.
Product Specifications
Dabrafenib
Formula: C23H20F3N5O2S2
MW: 519.56 g/mol
Storage/Handling: Store desiccated at room temperature.
PubChem Chemical ID: 44462760
