Description
Doxorubicin HCl is an anthracycline antibiotic that inhibits cancer progression by suppressing DNA replication. It is the 12-hydroxylated form of daunorubicin and causes DNA intercalation. It also inhibits topoisomerase II. Doxorubicin is researched for its efficacy against non-Hodgkin’s lymphoma, multiple myeloma, acute leukemias, Kaposi sarcoma, Wilm tumor, Ewing sarcoma, and cancers of the breast, lung, ovary, endometrium, and adrenal cortex. Doxorubicin is an MRP-1 substrate and has been used in drug-resistance studies.
Product Specifications
Doxorubicin HCl, USP Grade
Formula: C27H29NO11 ∙ HCl
MW: 579.98 g/mol
Storage/Handling: Store desiccated at 2-8 °C. Protect from light.
PubChem Chemical ID: 443939
Powered by Bioz