Description
Doxycycline hyclate is a semisynthetic tetracycline antibiotic effective against bacteria such as Mycoplasma pneumoniae and Haemophilus influenzae. It is also a broad-spectrum inhibitor of matrix metalloproteases (MMPs). Doxycycline hyclate is routinely used to select for cells containing the pcDNA3.1 resistance plasmid in cell line 293 at an effective concentration of 2 μg/mL. It is freely soluble in aqueous solution.
Tetracyclines are antibiotics made up of a four-ring system. They bind the 30s ribosomal subunit, preventing the aminoacyl-tRNA from attaching to the A site. Consequently, protein synthesis is inhibited.
Product Specifications
Doxycycline Hyclate
MOLECULAR BIOLOGY GRADE
Formula: C22H24N2O8 ∙ HCl ∙ ½(H2O) ∙ ½(C2H6O)
MW: 512.94 g/mol
Storage/Handling: Store at 2-8°C. Product is light sensitive.
PubChem Chemical ID: 54686183
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