Doxycycline Hyclate

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Description

Doxycycline hyclate is a semisynthetic tetracycline antibiotic effective against bacteria such as Mycoplasma pneumoniae and Haemophilus influenzae. It is also a broad-spectrum inhibitor of matrix metalloproteases (MMPs). Doxycycline hyclate is routinely used to select for cells containing the pcDNA3.1 resistance plasmid in cell line 293 at an effective concentration of 2 μg/mL. It is freely soluble in aqueous solution.

Tetracyclines are antibiotics made up of a four-ring system. They bind the 30s ribosomal subunit, preventing the aminoacyl-tRNA from attaching to the A site. Consequently, protein synthesis is inhibited.


Product Specifications
Doxycycline Hyclate

MOLECULAR BIOLOGY GRADE

Formula: C22H24N2O8 ∙ HCl ∙ ½(H2O) ∙ ½(C2H6O)

MW: 512.94 g/mol

Storage/Handling: Store at 2-8°C. Product is light sensitive.

PubChem Chemical ID: 54686183

Doxycycline Hyclate

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Catalog Number:
D-500-1
CAS Number:
24390-14-5
$32.00

For research use only. Not for food, drug, household, or cosmetic use.
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In stock
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$14.99 Ground shipping (In continental US only.)

    Description

    Doxycycline hyclate is a semisynthetic tetracycline antibiotic effective against bacteria such as Mycoplasma pneumoniae and Haemophilus influenzae. It is also a broad-spectrum inhibitor of matrix metalloproteases (MMPs). Doxycycline hyclate is routinely used to select for cells containing the pcDNA3.1 resistance plasmid in cell line 293 at an effective concentration of 2 μg/mL. It is freely soluble in aqueous solution.

    Tetracyclines are antibiotics made up of a four-ring system. They bind the 30s ribosomal subunit, preventing the aminoacyl-tRNA from attaching to the A site. Consequently, protein synthesis is inhibited.


    Product Specifications
    Doxycycline Hyclate

    MOLECULAR BIOLOGY GRADE

    Formula: C22H24N2O8 ∙ HCl ∙ ½(H2O) ∙ ½(C2H6O)

    MW: 512.94 g/mol

    Storage/Handling: Store at 2-8°C. Product is light sensitive.

    PubChem Chemical ID: 54686183

    Product Specifications

    Catalog ID: D-500
    CAS #: 24390-14-5
    MW: 512.94 g/mol
    Grade: MOLECULAR BIOLOGY GRADE
    Storage/handling: Store at 4°C.
    PubChem Chemical ID: 54686183
    IUPAC Name: bis((4S,4aR,5S,5aR,6R,12aR)-4-(dimethylamino)-1,5,10,11,12a-pentahydroxy-6-methyl-3,12-dioxo-4a,5,5a,6-tetrahydro-4H-tetracene-2-carboxamide);ethanol;hydrate;dihydrochloride
    InChI: InChI=1S/2C22H24N2O8.C2H6O.2ClH.H2O/c2*1-7-8-5-4-6-9(25)11(8)16(26)12-10(7)17(27)14-15(24(2)3)18(28)13(21(23)31)20(30)22(14,32)19(12)29;1-2-3;;;/h2*4-7,10,14-15,17,25-27,30,32H,1-3H3,(H2,23,31);3H,2H2,1H3;2*1H;1H2/t2*7-,10+,14+,15-,17-,22-;;;;/m00..../s1
    InChIKey: UHHHTIKWXBRCLT-VDBOFHIQSA-N
    SMILES: CCO.CC1C2C(C3C(C(=O)C(=C(C3(C(=O)C2=C(C4=C1C=CC=C4O)O)O)O)C(=O)N)N(C)C)O.CC1C2C(C3C(C(=O)C(=C(C3(C(=O)C2=C(C4=C1C=CC=C4O)O)O)O)C(=O)N)N(C)C)O.O.Cl.Cl

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