Description
Erlotinib HCl is an anti-cancer agent targeting epidermal growth factor receptor (EGFR) tyrosine kinase ATP binding sites, which are commonly overexpressed and sometimes mutated in a variety of cancers. Erlotinib prevents the formation of EGFR homodimers leading to suppression of signal transmittance and tumor growth inhibition. Additionally, erlotinib suppresses cyclin-dependent kinase 2 (Cdk2). It has been shown to be effective against non-small cell lung cancer and pancreatic cancer.
Product Specifications
Erlotinib HCl
Tarceva®
MOLECULAR BIOLOGY GRADE
Formula: C22H23N3O4
MW: 393.44 g/mol
Storage/Handling: Store at 2-8 °C. Product is soluble in acid (pH 2) at 0.4 mg/mL.
PubChem Chemical ID: 176870
Air shipments may require special packaging and a small additional box charge.
