Description
Florfenicol, like chloramphenicol, is a bacteriostatic antibiotic and an analog of thiamphenicol. It targets gram-negative and gram-positive bacteria, especially those responsible for bovine respiratory infections. Florfenicol is soluble in water and lipid solvents.
Florfenicol works by binding the 50s ribosomal subunit, inhibiting peptide bonds from forming. Decreased cell permeability or a 50s ribosomal subunit mutation may confer resistance to florfenicol.
Antibiotics are often used in clinical in vitro tests known as antimicrobial susceptibility tests or ASTs to determine their efficacy against certain bacterial species. They are tested against gram-negative and gram-positive bacteria using panels, discs, and MIC strips by medical microbiologists. ASTs decrease the risk of using an antibiotic against bacteria exhibiting resistance to it, and the results are used in clinical settings to determine which antibiotic(s) to prescribe for various infections.
Product Specifications
Florfenicol
MOLECULAR BIOLOGY GRADE
Formula: C12H14Cl2FNO4S
MW: 358.21 g/mol
Storage/Handling: Store at 4°C. This product is soluble in lipids and water.
PubChem Chemical ID: 114811
