Gefitinib

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Description

Gefitinib is an anti-cancer agent similar to erlotinib. It functions through inhibiting the overexpressed or mutated epidermal growth factor receptor (EGFR) by binding its ATP binding site. Overexpression and mutation of EGFR are common in cancer cell lines and may lead to uncontrolled proliferation through the Ras signaling cascade. Gefitinib has been shown to induce tumor cell apoptosis in HaCaT cells, KG-1 cells, P39 cells, and CD34+ myeloblasts. Additionally, it has been shown to promote keratinocyte apoptosis.

Product Specifications
Gefitinib
Iressa®

MOLECULAR BIOLOGY GRADE

Formula: C22H24ClFN4O3

MW: 446.90 g/mol

Storage/Handling: Store at - 20 °C.

PubChem Chemical ID: 123631

Gefitinib

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Catalog Number:
G-610-100
CAS Number:
184475-35-2
$66.00

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    Description

    Gefitinib is an anti-cancer agent similar to erlotinib. It functions through inhibiting the overexpressed or mutated epidermal growth factor receptor (EGFR) by binding its ATP binding site. Overexpression and mutation of EGFR are common in cancer cell lines and may lead to uncontrolled proliferation through the Ras signaling cascade. Gefitinib has been shown to induce tumor cell apoptosis in HaCaT cells, KG-1 cells, P39 cells, and CD34+ myeloblasts. Additionally, it has been shown to promote keratinocyte apoptosis.

    Product Specifications
    Gefitinib
    Iressa®

    MOLECULAR BIOLOGY GRADE

    Formula: C22H24ClFN4O3

    MW: 446.90 g/mol

    Storage/Handling: Store at - 20 °C.

    PubChem Chemical ID: 123631

    Product Specifications

    Catalog ID: G-610
    CAS #: 184475-35-2
    MW: 446.90 g/mol
    Grade: MOLECULAR BIOLOGY GRADE
    Storage/handling: Store at -20°C.

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