Description
GoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption!
Recombinant Human Interferon lambda 1
IFNL1
Interleukin 29 (IL29)
Interferon lambda 1, also known as interleukin 29, belongs to the newly classified type III interferon family. Expression of IFNL1 is seen in a variety of cell types in response to viral infection or treatment with double-stranded RNA. IFNL1 exerts antiviral activity and upregulation of MHC class I antigen expression. It signals through a heterodimeric receptor complex composed of IL10RB and IFNLR1 which activates the JAK-STAT pathway, phosphorylating STAT1, STAT2, and STAT3.
Sterile Filtered White lyophilized powder. Purified and tested for use in cell culture.
Source: Escherichia coli
MW: ~19.8 kDa (181 amino acids)
Purity: >97% by SDS-PAGE and HPLC analyses
Biological Activity: Fully biologically active when compared to standard. The ED50 as determined by an anti-viral assay using human HepG2 cells infected with encephalomyocarditis is less than 5 ng/ml, corresponding to specific activity of >2.0×105 IU/mg.
Storage/Handling: Store desiccated at -20°C.
HGNC: 18363
NOT FOR HUMAN USE!
Additional resources for this protein may be found at:
OMIM
