Description
GoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption!
Recombinant Murine Interleukin-13
IL13
Interleukin 13
Interleukin-13 (IL13) is an immunoregulatory cytokine produced primarily by activated Th2 cells, along with mast cells and NK cells. Targeted deletion of IL13 in mice resulted in impaired Th2 cell development and indicated that IL13 plays an important role in the expulsion of gastrointestinal parasites. IL13 exerts anti-inflammatory effects on monocytes and macrophages and inhibits the expression of inflammatory cytokines such as IL1β, TNF-α, IL6 and IL8. IL13 has also been shown to enhance B-cell proliferation and to induce isotype switching which results in an increased production of IgE. It has been suggested that the blocking of IL13 and its downstream effectors could play a role in the mechanism of asthma. Human and murine IL13 are cross-species reactive.
Sterile Filtered White Lyophilized Powder. Purified and tested for use in cell culture.
Source: Escherichia coli
MW: ~12.3 kDa (111 amino acids)
Purity: >97% by SDS-PAGE and HPLC analyses.
Storage/Handling: Store desiccated at -20°C.
NOT FOR HUMAN USE!
MGI: 96541
Cross-species Homology
Percent Similarity:
| | HuIL13 | MuIL13 | RtIL13 |
| HuIL13 | *** | 57.0 | 60.2 |
| MuIL13 | *** | *** | 76.1 |
| RtIL13 | *** | *** | *** |
Additional resources for this protein may be found at:
OMIM
