Description
GoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption!
Recombinant Rat Interleukin-4
IL4
Interleukin 4
B-Cell Stimulatory Factor 1 (BSF1)
Interleukin-4 (IL4) is a pleiotropic cytokine that induces differentiation of naive helper T-cells (Th0 cells) to Th2-cells, and is produced by mast cells, activated T-cells and bone marrow stromal cells. It has many biological roles, including the stimulation of activated B-cell and T-cell proliferation, and the differentiation of CD4+ T-cells into Th2-cells. IL4 can enhance both the secretion and cell surface expression of IgE and IgG1. IL4 also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. The rat IL4 shares about 40-45% amino acid sequence identity with human, mouse, rhesus macaque IL4, and they are species-specific in their activities.
Sterile Filtered White Lyophilized Powder. Purified and tested for use in cell culture.
Source: Escherichia coli
MW: ~14.0 kDa (125 amino acids)
Purity: >95% by SDS-PAGE and HPLC analyses.
Storage/Handling: Store desiccated at -20°C.
NOT FOR HUMAN USE!
Rat Genome Database ID: 2898
Cross-species homology
Percent Similarity
| | HuIL4 | MuIL4 | RtIL4 |
| HuIL4 | *** | 40.9 | 42.4 |
| MuIL4 | *** | *** | 62.4 |
| RtIL4 | *** | *** | *** |
Additional resources for this protein may be found at:
OMIM
Note: 1000 µg volume may be delivered in multiple containers.
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