Description
GoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption!
Recombinant Murine Interleukin-7
IL7
Interleukin 7
Interleukin-7 (IL7) is encoded by the IL7 gene and secreted by stromal cells in the red marrow and thymus. IL7 binds to the IL7 receptor, a heterodimer consisting of IL7 receptor alpha and IL2 receptor gamma chain. IL7 stimulates the differentiation of hematopoietic stem cells into lymphoid progenitor cells. It also stimulates the proliferation of B-cells, T-cells and NK cells. Murine IL7 has approximately 61% and 88% amino acid sequence identity with human and rat IL7, and both proteins exhibit cross-species activity. IL7 as an immunotherapy agent has been examined in many human clinical trials for various malignancies and during HIV infection.
Sterile Filtered White Lyophilized Powder. Purified and tested for use in cell culture.
Source: Escherichia coli
MW: ~21.7 kDa (187 amino acids)
Purity: >97% by SDS-PAGE and HPLC analyses.
Storage/Handling: Store desiccated at -20°C.
NOT FOR HUMAN USE!
MGI: 96561
Cross-species Homology
Percent Similarity:
| | HuIL7 | MuIL7 | RtIL7 |
| HuIL7 | *** | 61.4 | 62.6 |
| MuIL7 | *** | *** | 88.3 |
| RtIL7 | *** | *** | *** |
Additional resources for this protein may be found at:
OMIM
Note: 1000 µg volume may be delivered in multiple containers.
