Description
GoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption!
Recombinant Human Interleukin-8, 77 a.a.
HuIL8
Chemokin, CXC Motif, Ligand 8 (CXCL8)
Monocyte-Derived Neutrophil Chemotactic Factor
Small Inducible Cytokine Subfamily B, Member (SCYB8)
Interleukin-8 (IL8) is encoded by the IL8 gene and produced by macrophages and other cell types such as epithelial cells. There are many receptors capable of binding to IL8; however, the molecules with the highest affinity to IL8 are receptors CXCR1 and CXCR2. As a member of the CXC chemokine family, one of the functions of IL8 is the induction of chemotaxis in its target cells, like neutrophil granulocytes, basophils and T-cells. IL8 (72a.a.) has a 5-10-fold higher activity on neutrophil activation, compared to IL8 (77 a.a.). IL8 is often associated with inflammation, and has been cited as a pro-inflammatory mediator in gingivitis and psoriasis.
Sterile Filtered White Lyophilized Powder. Purified and tested for use in cell culture.
Source: Escherichia coli
MW: ~8.9 kDa (77 amino acids)
Purity: >96% by SDS-PAGE and HPLC analyses.
Storage/Handling: Store desiccated at -20°C.
NOT FOR HUMAN USE!
HGNC: 6025
Additional resources for this protein may be found at:
OMIM
