Description
Through inhibition of superoxide dismutase, IPA has shown to protect against oxidative damage in primary neurons and neuroblastoma cells. IPA has also shown to protect against death caused by exposure to amyloid β-protein in primary neurons and neuroblastoma cells.
Product Specifications
IPA
Indole-3-propionic acid
3-(3-Indolyl)propanoic acid
MOLECULAR BIOLOGY GRADE
Formula: C11H11NO2
MW: 189.22 g/mol
Color: Off-white to yellowish crystalline powder
Storage/Handling: Store at -20°C. Protect from light.
PubChem CID: 3744
Selected References
Chyan Y., Poeggeler B., Omar R.A., Chain D.G., Frangione B., Ghiso J., Pappolla M.A. (1999). Potent Neuroprotective Properties against the Alzheimer Amyloid by an Endogenous Melatonin-related Indole Structure, Indole-3-propionic Acid. J. Biol. Chem 274: 21937-42.
