Isoniazid

Description

Isoniazid is a prodrug derivative of nicotinic acid that is used as an antibiotic compound against Mycobactrium tuberculosis, M. bovis, and other mycobacteria. This prodrug is transformed by catalase-peroxidases, where its active form inhibits an enoyl-reductase (InhA). Inhibition of InhA compromises bacterial cell walls by preventing mycolic acid synthesis, disrupting fluid homeostasis and leading to cell death.

Product Specifications
Isoniazid
Isonicotinic acid hydrazide

Formula: C6H7N3O

MW: 137.14 g/mol

Storage/Handling: Store at room temperature.

PubChem Chemical ID: 3767

Isoniazid

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Catalog Number:
I-450-100
CAS Number:
54-85-3
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    Description

    Isoniazid is a prodrug derivative of nicotinic acid that is used as an antibiotic compound against Mycobactrium tuberculosis, M. bovis, and other mycobacteria. This prodrug is transformed by catalase-peroxidases, where its active form inhibits an enoyl-reductase (InhA). Inhibition of InhA compromises bacterial cell walls by preventing mycolic acid synthesis, disrupting fluid homeostasis and leading to cell death.

    Product Specifications
    Isoniazid
    Isonicotinic acid hydrazide

    Formula: C6H7N3O

    MW: 137.14 g/mol

    Storage/Handling: Store at room temperature.

    PubChem Chemical ID: 3767

    Product Specifications

    Catalog ID: I-450
    CAS #: 54-85-3
    MW: 137.14 g/mol
    Storage/handling: Store at room temperature.

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