Kasugamycin HCl

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Description

Kasugamycin HCl is an aminoglycoside antibiotic used to combat yeast and pathogenic fungi such as M. grisea. It has been isolated from Streptomyces kasugaensis. Kasugamycin has been used to prevent and treat M. grisea mycelia formation in rice and against parasitic infections of plants such as leaf spot or apple scab. It is the antibiotic of choice in many infections due to its low phytotoxicity. Additionally, kasugamycin has been used to study ribosome structure and kasugamycin resistance.

Aminoglycoside antibiotics are composed of amino groups attached to glycosides. They bind the 30s ribosomal subunit, causing misreading of the mRNA sequence and inhibition of translocation. Consequently, protein synthesis is inhibited.

Product Specifications
Kasugamycin HCl

Kasugamycin hydrochloride

MOLECULAR BIOLOGY GRADE

Formula: C14H25N3O9 ∙ HCl

MW: 415.82 g/mol

Storage/Handling: Store at 2-8 °C.
Solubility of the product increases with pH.

PubChem Chemical ID: 88045

Kasugamycin HCl

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Catalog Number:
K-200-1
CAS Number:
19408-46-9
$82.00

For research use only. Not for food, drug, household, or cosmetic use.
Availability:
2-3 Weeks
Shipping:
$14.99 Ground shipping (In continental US only.)

    Description

    Kasugamycin HCl is an aminoglycoside antibiotic used to combat yeast and pathogenic fungi such as M. grisea. It has been isolated from Streptomyces kasugaensis. Kasugamycin has been used to prevent and treat M. grisea mycelia formation in rice and against parasitic infections of plants such as leaf spot or apple scab. It is the antibiotic of choice in many infections due to its low phytotoxicity. Additionally, kasugamycin has been used to study ribosome structure and kasugamycin resistance.

    Aminoglycoside antibiotics are composed of amino groups attached to glycosides. They bind the 30s ribosomal subunit, causing misreading of the mRNA sequence and inhibition of translocation. Consequently, protein synthesis is inhibited.

    Product Specifications
    Kasugamycin HCl

    Kasugamycin hydrochloride

    MOLECULAR BIOLOGY GRADE

    Formula: C14H25N3O9 ∙ HCl

    MW: 415.82 g/mol

    Storage/Handling: Store at 2-8 °C.
    Solubility of the product increases with pH.

    PubChem Chemical ID: 88045

    Product Specifications

    Catalog ID: K-200
    CAS #: 19408-46-9
    Formula: C14H25N3O9∙HCl
    MW: 415.82 g/mol
    Grade: MOLECULAR BIOLOGY GRADE
    Storage/handling: Store at 4°C.
    PubChem Chemical ID: 88045
    IUPAC Name: 2-amino-2-[(2R,3S,5S,6R)-5-amino-2-methyl-6-[(2R,3S,5S,6S)-2,3,4,5,6-pentahydroxycyclohexyl]oxyoxan-3-yl]iminoacetic acid;hydrochloride
    InChI: InChI=1S/C14H25N3O9.ClH/c1-3-5(17-12(16)13(23)24)2-4(15)14(25-3)26-11-9(21)7(19)6(18)8(20)10(11)22;/h3-11,14,18-22H,2,15H2,1H3,(H2,16,17)(H,23,24);1H/t3-,4+,5+,6?,7+,8+,9-,10+,11?,14-;/m1./s1
    InChIKey: ZDRBJJNXJOSCLR-YZKQBBCCSA-N
    SMILES: CC1C(CC(C(O1)OC2C(C(C(C(C2O)O)O)O)O)N)N=C(C(=O)O)N.Cl

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