Description
Homocysteine is a cysteine homolog that differs by having an additional methylene bridge. It is often used in vitro as a reference to measure L-homocysteine in plasma in order to diagnose homocystinuria. This genetic disorder causes the body to be unable to process certain amino acids.
Homocysteine is biosynthesized from methionine through the intermediate S-adenosylmethionine. Homocysteine can then be converted to cysteine or back to methionine. The conversion to cysteine requires vitamin B6 as a cofactor while the conversion back to methionine requires vitamin B12. Increased levels of homocysteine in plasma can occur because of a vitamin B deficiency.
Product Specifications
L-Homocysteine
MOLECULAR BIOLOGY GRADE
Formula: C4H9NO2S
MW: 135.19 g/mol
Color/Purity: White to off-white crystalline powder
Storage/Handling: Store in -20°C. Protect from light.
PubChem Chemical ID: 91552
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