Description
Mitomycin C is an antineoplastic antibiotic isolated from Streptomyces caespitosus. It is effective against gram-negative and gram-positive bacteria and a variety of cancer cells, including Ehrlich ascites tumor cells. Mitomycin C has been used to produce mitotically inactivated feeder cells and has been shown to increase recombination during fruit fly meiosis. It is capable of killing mutant strains of Arabidopsis that are defective for recombination during meiosis.
Mitomycin C functions as a DNA crosslinking agent, inhibiting DNA synthesis.
Product Specifications
Mitomycin C, USP Grade
Formula: C15H18N4O5
MW: 334.33 g/mol
Storage/Handling: Store at 4°C.
Soluble in water up to 0.5 mg/ml.
PubChem Chemical ID: 5746
Air shipments may require special packaging and a small additional box charge.
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