Description
 Nigericin is an ionophore antibiotic isolated from Streptomyces hygroscopicus.  It has been shown to suppress DNA synthesis in Ehrlich ascites carcinoma.  Nigericin is insoluble in water, but soluble in methanol and chloroform. 
  Nigericin sodium disrupts membrane potential by acting as an antiporter of H+ and K+ ions by exchanging K+ for H+.  This causes a rapid decrease in intracellular pH. 
  Product Specifications
 Nigericin Sodium Salt 
  MOLECULAR BIOLOGY GRADE 
  Formula: C40H67NaO11 
  MW: 746.94 g/mol 
  Storage/Handling: Store at 2-8°C.
 This product is soluble in chloroform and methanol. 
  PubChem Chemical ID: 23681158