Description
Oxolinic acid is a synthetic quinolone antibiotic targeting gram-negative bacteria, especially those responsible for causing urinary tract infections. It has also been reported to be effective against Burkholderia glumae, a bacteria causing grain rot, sheath rot, seedling rot, and bacterial panicle blight. It has been useful in studying transmissible resistance mechanisms of E. coli and S. enterica. It can be used to isolate Gardnerella vaginalis and as a dopamine reuptake inhibitor in neurological research.
Oxolinic acid functions by inhibiting DNA gyrase or topoisomerase II, enzymes essential for DNA synthesis. Oxolinic acid is insoluble in water but is soluble in dilute alkali solutions.
Product Specifications
Oxolinic Acid
MOLECULAR BIOLOGY GRADE
Formula: C13H11NO5
MW: 261.23 g/mol
Storage/Handling: Store at 2-8°C.
This product is light sensitive, and is soluble in 0.5N NaOH with heat.
PubChem Chemical ID: 4628
