Description
Perfloxacin is a fluoroquinolone antibiotic and is an analog of norfloxacin. It targets gram-negative and gram-positive bacteria as well as several Mycoplasma species. It is commonly used against Gonococcal species and to induce achilles tendon toxicity in rodents.
Fluoroquinolones are a group of broad-spectrum antibiotics that inhibit DNA synthesis. These antibiotics prevent unwinding of double-stranded DNA by binding DNA gyrase or DNA topoisomerase. By preventing the formation of single-stranded DNA, fluoroquinolones inhibit bacterial replication.
Antibiotics are often used in clinical in vitro tests known as antimicrobial susceptibility tests or ASTs to determine their efficacy against certain bacterial species. They are tested against gram-negative and gram-positive bacteria using panels, discs, and MIC strips by medical microbiologists. ASTs decrease the risk of using an antibiotic against bacteria exhibiting resistance to it, and the results are used in clinical settings to determine which antibiotic(s) to prescribe for various infections.
Product Specifications
Pefloxacin Mesylate Dihydrate
MOLECULAR BIOLOGY GRADE
Formula: C17H20FN3O3 ∙ CH4O3S ∙ 2H2O
MW: 465.49 g/mol
Storage/Handling: Store at 2-8°C. This product is light sensitive.
PubChem Chemical ID: 6917670
